DeepMind and Isomorphic Labs unveil AlphaFold 3

Google DeepMind and Isomorphic Labs announced AlphaFold 3 on 8 May 2024, extending the protein-structure predictor to complexes of proteins with DNA, RNA, small-molecule ligands, and ions. The Nature paper reported at least a 50% accuracy gain over prior methods.

Why it mattered Modeling how proteins bind DNA, RNA, and drug-like molecules moved AlphaFold from structural biology toward drug discovery, the work Isomorphic Labs was formed to sell.